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Naupastad 10

Naupastad 10

domperidone

Manufacturer:

Stellapharm

Distributor:

HK Medical Supplies
/
Health Express
Concise Prescribing Info
Contents
Domperidone maleate
Indications/Uses
Symptomatic relief of nausea & vomiting in adults & adolescents ≥12 yr & weighing ≥35 kg.
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Dosage/Direction for Use
Adult & adolescent ≥12 yr & weighing ≥35 kg 1 tab tds. Max dose: 30 mg daily. Max duration: 1 wk.
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Overdosage
View Naupastad 10 overdosage for action to be taken in the event of an overdose.
Administration
Should be taken on an empty stomach.
Contraindications
Hypersensitivity. Prolactin-releasing pituitary tumor (prolactinoma). Harmful stimulation of gastric motility eg, in patients w/ GI haemorrhage, mechanical obstruction or perforation. Patients w/ known existing prolongation of cardiac conduction intervals, particularly QTc; significant electrolyte disturbances or underlying cardiac diseases eg, CHF. Co-administration w/ QT-prolonging drugs; potent CYP3A4 inhibitors. Patients w/ moderate or severe hepatic impairment.
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Special Precautions
Use at the lowest effective dose for the shortest duration. QT interval prolongation. Increased risk of serious ventricular arrhythmias or sudden cardiac death. Stop treatment in case of signs or symptoms that may be associated w/ cardiac arrhythmia. Patients w/ rare hereditary problems of galactose intolerance, total lactase deficiency or glucose-galactose malabsorption; severe renal impairment. Pregnancy & lactation. Childn <12 yr. Adolescents ≥12 yr & weighing <35 kg.
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Drug Interactions
Increased plasma levels w/ CYP3A4 inhibitors (potent CYP3A4 inhibitors eg, PIs, systemic azole antifungals, erythromycin, clarithromycin, telithromycin; moderate CYP3A4 inhibitors eg, diltiazem, verapamil & some macrolides). Increased risk of occurrence of QT-interval prolongation w/ QTc-prolonging medicinal products eg, disopyramide, hydroquinidine, quinidine, amiodarone, dofetilide, dronedarone, ibutilide, sotalol, haloperidol, pimozide, sertindole, citalopram, escitalopram, erythromycin, levofloxacin, moxifloxacin, spiramycin, pentamidine, halofantrine, lumefantrine, cisapride, dolasetron, prucalopride, mequitazine, mizolastine, toremifene, vandetanib, vincamine, bepridil, diphemanil, methadone, apomorphine. Caution w/ bradycardia- & hypokalaemia-inducing drugs, azithromycin, roxithromycin.
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Storage
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Description
View Naupastad 10 description for details of the chemical structure and excipients (inactive components).
MIMS Class
Antiemetics / GIT Regulators, Antiflatulents & Anti-Inflammatories
ATC Classification
A03FA03 - domperidone ; Belongs to the class of propulsives. Used in the treatment of functional gastrointestinal disorders.
Presentation/Packing
Form
Naupastad 10 FC tab 10 mg
Packing/Price
10 × 10's
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